Functional pattern of sacral root stimulation in dogs. II. Urethral closure

J Urol. 1982 May;127(5):1034-8. doi: 10.1016/s0022-5347(17)54183-x.

Abstract

Ten dogs were used for electrostimulation of the sacral roots to improve urethral sphincter closure. To induce and maintain urethral closure in longstanding stimulation, a variety of stimulation patterns was investigated systematically. With continuous stimulation, the induced sphincteric response faded corresponding with the increase in frequency of stimulation applied, but in phasic stimulation with a stimulation/rest ratio of 1:2, strong sphincteric contractions were reproducible after each rest interval. If the stimulation bursts were shortened to 30-60 msec., interrupted by an off-time of again twice the duration of the stimulation, unfused sphincteric tetani were induced, resulting in a sinusoidal oscillating closure pressure that did not drop in the prestimulus baseline during the off-time. A sufficient sphincteric closure pressure could thus be sustained over 1 hour of uninterrupted stimulation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Dogs
  • Electric Stimulation
  • Female
  • Male
  • Muscle Contraction
  • Pressure
  • Sacrococcygeal Region
  • Spinal Nerve Roots / physiology*
  • Urethra / physiology*