Abstract
Histocompatibility antigen testing has been carried out in 20 unrelated normotensive English Caucasoids with hypertrophic cardiomyopathy and in 17 relatives, six of whom also had the disease. A strong association with the HLA-DRw6 antigen complex was found (P = 0.0036) but it was no longer significant after correction for the 52 antigens tested (P = 0.1701).
MeSH terms
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Adolescent
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Adult
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Aged
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Cardiomyopathy, Hypertrophic / epidemiology
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Cardiomyopathy, Hypertrophic / genetics
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Cardiomyopathy, Hypertrophic / immunology*
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Female
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Genes, MHC Class II
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HLA Antigens / genetics*
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HLA Antigens / immunology
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HLA-C Antigens
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HLA-DR Antigens
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Histocompatibility Antigens Class II / immunology
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Humans
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London
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Male
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Middle Aged
Substances
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HLA Antigens
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HLA-C Antigens
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HLA-DR Antigens
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Histocompatibility Antigens Class II