Abstract
A review of recent progress in the investigation of the following two problems is given: (a) the origin of actyl groups in the acetylcoenzyme A which is used for the synthesis of actylcholine in mammalian nerve cells; (b) the role of acetylcoenzyme A in the control of acetylcholine synthesis. The data reviewed are mainly those that have been published after the reviews by Quastel (1978), Tucek (1978) and Jope (1979).
MeSH terms
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ATP Citrate (pro-S)-Lyase / metabolism
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Acetyl Coenzyme A / metabolism*
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Acetylcholine / biosynthesis*
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Animals
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Choline O-Acetyltransferase / metabolism
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Corpus Striatum / metabolism
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Detergents / pharmacology
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Glucose / metabolism
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Humans
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Mitochondria / metabolism
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Nerve Endings / enzymology
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Neurons / metabolism*
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Synaptosomes / metabolism
Substances
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Detergents
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Acetyl Coenzyme A
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Choline O-Acetyltransferase
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ATP Citrate (pro-S)-Lyase
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Glucose
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Acetylcholine