Abstract
We report a primary endodermal sinus tumor (EST) of the right hemidiaphragm, presenting as a right-sided hemothorax in an 18-month-old female. Four operations were performed, the last three being indicated solely by an elevated level of serum alpha-fetoprotein (AFP). Cyclic chemotherapy with varying drug combinations together with irradiation therapy were not effective in controlling the disease. To our knowledge, this is the first instance of a primary EST arising from the diaphragm.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bleomycin / therapeutic use
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Combined Modality Therapy
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Cyclophosphamide / therapeutic use
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Dactinomycin / therapeutic use
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Doxorubicin / therapeutic use
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Female
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Humans
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Infant
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Mesonephroma / pathology
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Mesonephroma / therapy*
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Methotrexate / therapeutic use
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Pleural Neoplasms / pathology
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Pleural Neoplasms / therapy*
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Vincristine / therapeutic use
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alpha-Fetoproteins / blood
Substances
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alpha-Fetoproteins
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Bleomycin
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Dactinomycin
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Methotrexate