Abstract
The mechanisms underlying psychotropic drug interactions include alterations in gastrointestinal absorption, protein-binding, specific and nonspecific metabolic degradation, receptor interactions, and renal clearance. The risk of interactions can be minimized by detailed drug history-taking, use of rapid reference sources, patient education, and physician behaviors that include serious attention to somatic complaints, identification of "at risk" situations, and rational prescribing habits.
MeSH terms
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Antidepressive Agents / pharmacology
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Antidepressive Agents, Tricyclic / pharmacology
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Antipsychotic Agents / pharmacology
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Barbiturates / pharmacology
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Benzodiazepines / pharmacology
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Cardiovascular Agents / pharmacology
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Chloral Hydrate / pharmacology
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Drug Interactions
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Humans
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Hydroxyzine / pharmacology
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Lithium / pharmacology
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Monoamine Oxidase Inhibitors / pharmacology
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Phenothiazines / adverse effects
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Psychotropic Drugs / adverse effects
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Psychotropic Drugs / pharmacology*
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Risk
Substances
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Antidepressive Agents
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Antidepressive Agents, Tricyclic
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Antipsychotic Agents
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Barbiturates
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Cardiovascular Agents
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Monoamine Oxidase Inhibitors
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Phenothiazines
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Psychotropic Drugs
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Benzodiazepines
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Hydroxyzine
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Chloral Hydrate
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Lithium