An automated screening technique for the detection of sickle-cell haemoglobin

J Clin Pathol. 1972 Apr;25(4):330-4. doi: 10.1136/jcp.25.4.330.

Abstract

An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment.

MeSH terms

  • Anemia, Sickle Cell / blood
  • Anemia, Sickle Cell / diagnosis*
  • Autoanalysis*
  • Buffers
  • Diagnosis, Differential
  • Hemoglobin C Disease / blood
  • Hemoglobinometry / instrumentation
  • Hemoglobins, Abnormal / analysis*
  • Humans

Substances

  • Buffers
  • Hemoglobins, Abnormal