Comparison of blood clearance of ethanol and tolbutamide and the activity of hepatic ethanol-oxidizing and drug-metabolizing enzymes in chronic alcoholic subjects

Am J Clin Nutr. 1972 Feb;25(2):135-9. doi: 10.1093/ajcn/25.2.135.
No abstract available

MeSH terms

  • Adult
  • Alcohol Oxidoreductases / metabolism
  • Alcoholism / enzymology
  • Alcoholism / metabolism*
  • Aniline Compounds
  • Chronic Disease
  • Ethanol / blood
  • Ethanol / metabolism*
  • Half-Life
  • Humans
  • Liver / enzymology*
  • Metabolic Clearance Rate
  • Microsomes, Liver / enzymology
  • Mixed Function Oxygenases / metabolism
  • Pentobarbital
  • Time Factors
  • Tolbutamide / blood*

Substances

  • Aniline Compounds
  • Ethanol
  • Tolbutamide
  • Mixed Function Oxygenases
  • Alcohol Oxidoreductases
  • Pentobarbital