[Effect of new quaternary imino compounds against selected bacterial and fungal strains. 11. Synthesis of 1-methyl- and 1-ethyl-3-(n-alkoxymethyl)imidazolium chlorides]

Pharmazie. 1985 Aug;40(8):570-1.
[Article in German]

Abstract

Syntheses and antibacterial activity of the imidazolium compounds are described. Syntheses of the imidazolium chlorides were performed by reaction of 1-alkylimidazole with chloromethylalkyl ether. Antibacterial properties of obtained compounds was tested on 13 strains of bacteria and fungi. Chlorides with n-dodecaoxymethyl radical indicated the best antibacterial activity.

Publication types

  • English Abstract

MeSH terms

  • Anti-Bacterial Agents
  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / pharmacology
  • Antifungal Agents / chemical synthesis*
  • Antifungal Agents / pharmacology
  • Bacteria / drug effects
  • Fungi / drug effects
  • Imidazoles / chemical synthesis*
  • Imidazoles / pharmacology
  • Structure-Activity Relationship

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antifungal Agents
  • Imidazoles
  • 1-methylimidazole