Precocious puberty and hypothalamic hamartoma. Report on a new case with ultrastructural data

Acta Neurochir (Wien). 1985;74(3-4):129-33. doi: 10.1007/BF01418802.

Abstract

A new case of hypothalamic hamartoma associated with precocious puberty is presented. After reviewing the literature, 23 other cases appeared. The ultrastructural study of the present case revealed common features with other hamartomatous lesions of the central nervous system and with the gangliogliomas. The data suggest that these lesions are morphologically organized in a very similar manner despite their very different growing potential.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Follicle Stimulating Hormone / blood
  • Hamartoma / complications*
  • Hamartoma / surgery
  • Hamartoma / ultrastructure
  • Humans
  • Hypothalamic Neoplasms / complications*
  • Hypothalamic Neoplasms / surgery
  • Hypothalamic Neoplasms / ultrastructure
  • Luteinizing Hormone / blood
  • Male
  • Microscopy, Electron
  • Neuroglia / ultrastructure
  • Neurons / ultrastructure
  • Puberty, Precocious / etiology*
  • Puberty, Precocious / pathology
  • Puberty, Precocious / surgery
  • Testosterone / blood

Substances

  • Testosterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone