[Immunological status and somatotropic activity of the pituitary in combined abdominal injuries complicated by peritonitis]

Vestn Khir Im I I Grek. 1985 Nov;135(11):79-83.
[Article in Russian]

Abstract

Associated injuries of the abdomen result in peritonitis twice more often than isolated ones, the peritonitis having more severe course and being the cause of lethal outcomes in 57% of the victims. The immune deficient state is thought to be one of the causes responsible for the reduced resistance to infection and the development of peritonitis in the postshock period. Patients with associated traumas show a considerable inhibition of the immune system within several hours and an impairment of its regulation which grows during the next day. So, even at the early terms the operative methods must be similar to those used in operations for the developed peritonitis.

MeSH terms

  • Abdominal Injuries / complications
  • Abdominal Injuries / physiopathology*
  • Adult
  • B-Lymphocytes / immunology*
  • Female
  • Growth Hormone / metabolism*
  • Humans
  • Leukocyte Count
  • Lymphopenia / complications
  • Male
  • Peritonitis / etiology*
  • T-Lymphocytes / immunology*

Substances

  • Growth Hormone