WFUMB Guideline/Guidance on Liver Multiparametric Ultrasound: Part 1. Update to 2018 Guidelines on Liver Ultrasound Elastography

Giovanna Ferraioli; Richard Gary Barr; Annalisa Berzigotti; Ioan Sporea; Vincent Wai-Sun Wong; Thomas Reiberger; Thomas Karlas; Maja Thiele; Ana Carolina Cardoso; Oyekoya Taiwo Ayonrinde; Laurent Castera; Christoph Frank Dietrich; Hiroko Iijima; Dong Ho Lee; William Kemp; Claudia P Oliveira; Shiv Kumar Sarin

doi:10.1016/j.ultrasmedbio.2024.03.013

WFUMB Guideline/Guidance on Liver Multiparametric Ultrasound: Part 1. Update to 2018 Guidelines on Liver Ultrasound Elastography

Ultrasound Med Biol. 2024 May 17:S0301-5629(24)00142-X. doi: 10.1016/j.ultrasmedbio.2024.03.013. Online ahead of print.

Authors

Giovanna Ferraioli¹, Richard Gary Barr², Annalisa Berzigotti³, Ioan Sporea⁴, Vincent Wai-Sun Wong⁵, Thomas Reiberger⁶, Thomas Karlas⁷, Maja Thiele⁸, Ana Carolina Cardoso⁹, Oyekoya Taiwo Ayonrinde¹⁰, Laurent Castera¹¹, Christoph Frank Dietrich¹², Hiroko Iijima¹³, Dong Ho Lee¹⁴, William Kemp¹⁵, Claudia P Oliveira¹⁶, Shiv Kumar Sarin¹⁷

Affiliations

¹ Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. Electronic address: giovanna.ferraioli@unipv.it.
² Department of Radiology, Northeastern Ohio Medical University, Rootstown, Ohio, USA; Southwoods Imaging, Youngstown, Ohio, USA.
³ Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
⁴ Division of Gastroenterology and Hepatology, Department of Internal Medicine II, Center for Advanced Research in Gastroenterology and Hepatology, "Victor Babeș" University of Medicine and Pharmacy, Timișoara, Romania.
⁵ Medical Data Analytics Centre, Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong, China.
⁶ Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria; Christian-Doppler Laboratory for Portal Hypertension and Liver Fibrosis, Medical University of Vienna, Vienna, Austria.
⁷ Division of Gastroenterology, Department of Medicine II, Leipzig University Medical Center, Leipzig, Germany.
⁸ Center for Liver Research, Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark; Department for Clinical Research, University of Southern Denmark, Odense, Denmark.
⁹ Hepatology Division, School of Medicine, Federal University of Rio de Janeiro, Clementino, Fraga Filho Hospital, Rua Prof. Rodolpho Paulo Rocco, Cidade Universitária da Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
¹⁰ Department of Gastroenterology and Hepatology, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; Medical School, University of Western Australia, Crawley, Western Australia, Australia; Curtin Medical School, Curtin University, Kent Street, Bentley, Western Australia, Australia.
¹¹ Université Paris-Cité, Inserm UMR1149, Centre de Recherche sur l'Inflammation, Paris, France; Service d'Hépatologie, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, Clichy, France.
¹² Department Allgemeine Innere Medizin (DAIM), Kliniken Hirslanden Beau Site, Salem and Permancence, Bern, Switzerland.
¹³ Division of Hepatobiliary and Pancreatic Disease, Department of Gastroenterology, Hyogo Medical University, Nishinomiya, Hyogo, Japan; Ultrasound Imaging Center, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
¹⁴ Department of Radiology, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, Republic of Korea.
¹⁵ Department of Gastroenterology, Alfred Hospital, Melbourne, Australia; Department of Medicine, Central Clinical School, Monash University, Melbourne, Australia.
¹⁶ Gastroenterology Department, Laboratório de Investigação (LIM07), Hospital das Clínicas de São Paulo, HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
¹⁷ Department of Hepatology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi, India.

PMID: 38762390
DOI: 10.1016/j.ultrasmedbio.2024.03.013

Abstract

The World Federation for Ultrasound in Medicine and Biology (WFUMB) endorsed the development of this document on multiparametric ultrasound. Part 1 is an update to the WFUMB Liver Elastography Guidelines Update released in 2018 and provides new evidence on the role of ultrasound elastography in chronic liver disease. The recommendations in this update were made and graded using the Oxford classification, including level of evidence (LoE), grade of recommendation (GoR) and proportion of agreement (Oxford Centre for Evidence-Based Medicine [OCEBM] 2009). The guidelines are clinically oriented, and the role of shear wave elastography in both fibrosis staging and prognostication in different etiologies of liver disease is discussed, highlighting advantages and limitations. A comprehensive section is devoted to the assessment of portal hypertension, with specific recommendations for the interpretation of liver and spleen stiffness measurements in this setting.

Keywords: Acoustic radiation force impulse; Alcohol-related liver disease; Cirrhosis; Metabolic dysfunction-associated steatotic liver disease; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Pediatrics; Portal hypertension; Shear wave elastography; Vibration-controlled transient elastography.

Publication types

Review