[Cause analysis and clinical intervention of C 5 palsy after cervical surgery]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024 May 15;38(5):608-612. doi: 10.7507/1002-1892.202402006.
[Article in Chinese]

Abstract

Objective: To review the research progress of C 5 palsy (C 5P) after cervical surgery, providing new clinical intervention ideas for the C 5P patients.

Methods: The relevant literature domestically and abroad was extensively consulted and the latest developments in the incidence, risk factors, manifestations and diagnosis, prevention, and intervention measures of C 5P were systematically expounded.

Results: C 5P is characterized by weakness in the C 5 nerve innervation area after cervical decompression surgery, manifested as limited shoulder abduction and elbow flexion, with an incidence rate more than 5%, often caused by segmental spinal cord injury or mechanical injury to the nerve roots. For patients with risk factors, careful operation and preventive measures can reduce the incidence of C 5P. Most of the patients can recover with conservative treatment such as drug therapy and physical therapy, while those without significant improvement after 6 months of treatment may require surgical intervention such as foraminal decompression and nerve displacement.

Conclusion: Currently, there has been some advancement in the etiology and intervention of C 5P. Nevertheless, further research is imperative to assess the timing of intervention and surgical protocol.

目的: 综述颈椎术后C 5麻痹(C 5 palsy,C 5P)研究进展,为临床治疗C 5P患者提供参考。.

方法: 广泛查阅国内外颈椎术后C 5P相关文献,系统性阐述C 5P发病机制、危险因素、临床表现及诊断、预防、治疗措施新进展。.

结果: C 5P为颈椎术后出现的C 5神经支配区肌肉无力,表现为肩外展、屈肘受限,发生率>5%,可能由节段性脊髓损伤或神经根机械损伤导致。对于存在危险因素患者,术中仔细操作及采取预防性措施可减少术后C 5P的发生。大部分患者经药物治疗、物理治疗等保守治疗后功能可恢复,6个月以上无明显好转者可予以手术干预,可选用椎间孔减压、神经移位等手术方案。.

结论: 有关C 5P发病机制及预防措施等已取得一定研究进展,但对于干预时机和手术方式仍需进一步研究。.

Keywords: C5 palsy; cervical surgery; complication; nerve root injury.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Cervical Vertebrae* / surgery
  • Decompression, Surgical* / methods
  • Humans
  • Paralysis / etiology
  • Postoperative Complications* / etiology
  • Postoperative Complications* / prevention & control
  • Postoperative Complications* / therapy
  • Risk Factors
  • Spinal Cord Injuries / etiology
  • Spinal Cord Injuries / therapy
  • Spinal Nerve Roots

Grants and funding

国家自然科学基金资助项目(82072545);上海市科学技术委员会科技创新计划项目(22S31902100);科技创新2030-重大项目(2022ZD0208605、2022ZD0208600);上海市临床重点专科项目(shslczdzk05601)、上海市周围神经与显微外科重点实验室项目(20DZ2270200)