An Unusual Presentation of Membranous Nephropathy in an Adult With Arthrogryposis: A Case Report

Cureus. 2024 Apr 15;16(4):e58339. doi: 10.7759/cureus.58339. eCollection 2024 Apr.

Abstract

Membranous nephropathy (MN) is an autoimmune condition that is a common cause of nephrotic syndrome in nondiabetic adults. In this study, we highlight a case of a 22-year-old male with a past medical history of arthrogryposis multiplex congenita (AMC) who initially presented with right flank pain and hematuria. Subsequent workup revealed significant proteinuria with biopsy-proven primary MN. Early detection of the disease is critical to establish treatment promptly and prevent complications such as those resulting from a hypercoagulable state.

Keywords: arthrogryposis multiplex congenita; flank pain; hypercoagulable state; nephrotic-range proteinuria; primary membranous nephropathy.

Publication types

  • Case Reports