Frequency of vitamin D deficiency in children with iron deficiency anaemia and factors associated with vitamin D deficiency

J Pak Med Assoc. 2024 Apr;74(4):626-630. doi: 10.47391/JPMA.8042.

Abstract

Objective: To evaluate vitamin D deficiency in children with iron-deficiency anaemia, and to identify the risk factors for such deficiency.

Methods: The cross-sectional study was conducted at the Children's Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan, from October 2021 to March 2022, and comprised children aged 1-5 years who had been diagnosed with iron-deficiency anaemia. Quantitative variables, like age, height, weight, gender, socioeconomic status and sibling status, were controlled by stratification. Data was compared to assess the risk factors of vitamin D deficiency among the subjects. Data was analysed using SPSS 22.

Results: Of the 236 children with iron-deficiency anaemia, 159(67.5%) also had vitamin D deficiency; 95(59%) girls and 65(41%) boys. Overall, 104(65.4%) subjects were aged 4-5 years and 55(34.6%) were aged 1-3 years. Vitamin D deficiency had significant association with female gender, older age, height and weight <5th centiles, educated parents, low to middle socioeconomic status, urban residence and higher number of siblings (p<0.05).

Conclusions: The prevalence of vitamin D deficiency among children with iron-deficiency anaemia was found to be high.

Keywords: Anaemia, IDA, Vitamin D deficiency, Micronutrients deficiency, Risk factors..

MeSH terms

  • Age Factors
  • Anemia, Iron-Deficiency* / epidemiology
  • Body Height
  • Body Weight
  • Child, Preschool
  • Cross-Sectional Studies
  • Educational Status
  • Female
  • Humans
  • Infant
  • Male
  • Pakistan / epidemiology
  • Prevalence
  • Risk Factors
  • Sex Factors
  • Siblings
  • Social Class
  • Vitamin D Deficiency* / complications
  • Vitamin D Deficiency* / epidemiology