Proactive resistance management for sustaining the efficacy of RNA interference for pest control

Yulin Gao; Andrei Alyokhin; Runzhi Zhang; Guy Smagghe; Subba Reddy Palli; Juan Luis Jurat-Fuentes; Bruce E Tabashnik

doi:10.1093/jee/toae099

Proactive resistance management for sustaining the efficacy of RNA interference for pest control

J Econ Entomol. 2024 May 15:toae099. doi: 10.1093/jee/toae099. Online ahead of print.

Authors

Yulin Gao¹, Andrei Alyokhin², Runzhi Zhang³, Guy Smagghe^{4

5}, Subba Reddy Palli⁶, Juan Luis Jurat-Fuentes⁷, Bruce E Tabashnik⁸

Affiliations

¹ State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, PR China.
² School of Biology and Ecology, University of Maine, Orono, ME, USA.
³ Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, PR China.
⁴ Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
⁵ Institute of Entomology, Guizhou University, Guiyang 550025, PR China.
⁶ Department of Entomology, University of Kentucky, Lexington, KY, USA.
⁷ Department of Entomology and Plant Pathology, University of Tennessee, Knoxville, TN, USA.
⁸ Department of Entomology, University of Arizona, Tucson, AZ, USA.

PMID: 38748467
DOI: 10.1093/jee/toae099

Abstract

Biopesticides based on RNA interference (RNAi) took a major step forward with the first registration of a sprayable RNAi product, which targets the world's most damaging potato pest. Proactive resistance management is needed to delay the evolution of resistance by pests and sustain the efficacy of RNAi biopesticides.

Keywords: Colorado potato beetle; RNAi biopesticide; insect resistance management; integrated pest management.

© The Author(s) 2024. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.