International attitudes towards medical and planned oocyte cryopreservation

Stylianos Vagios; Bei Sun; John Yeh; Caitlin R Sacha

doi:10.1007/s10815-024-03116-7

International attitudes towards medical and planned oocyte cryopreservation

J Assist Reprod Genet. 2024 May 15. doi: 10.1007/s10815-024-03116-7. Online ahead of print.

Authors

Stylianos Vagios¹, Bei Sun², John Yeh³, Caitlin R Sacha^{4

5}

Affiliations

¹ Department of Obstetrics and Gynecology, Tufts Medical Center, 800 Washington Street, Boston, MA, USA. stylianos.vagios@tuftsmedicine.org.
² Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
³ Department of Obstetrics and Gynecology, Harvard Medical School, Boston, MA, USA.
⁴ Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Massachusetts Medical Center, Worcester, MA, USA.
⁵ Fertility Solutions, Dedham, MA, USA.

PMID: 38748360
DOI: 10.1007/s10815-024-03116-7

Abstract

Purpose: This study aims to better understand the knowledge and attitudes of men and women internationally towards oocyte cryopreservation (OC).

Methods: An online 25-question survey was distributed internationally via email and social media. Knowledge and attitudes towards OC among different regions and genders were assessed. The study population consisted of adults from North America (NA, 15.7%), Southeastern and Eastern Europe (SE, 34.7%), Central and Western Europe (CWE, 12.7%), Asia (12.7%), and Middle East (ME, 8.9%).

Results: A total of 496 respondents initiated the survey and the completion rate was 80.2%. The mean (SD) age was 35.2 (12.1) years. Over 70% were aware of OC, but only 4.8% had previously undergone the procedure. Most considered ages 26-31 as optimal for OC and correctly identified conditions that could impact the chance of spontaneous conception. Significant differences were observed regarding etiologies that would render OC acceptable. Only in NA and ME did solid majorities strongly agree that it is acceptable to proceed with OC to allow more time to find the right partner or for professional opportunities. More similar opinions were observed between genders. When medical conditions existed, large majorities across all nationalities and genders strongly agreed that OC is acceptable. In NA, SE, and ME most respondents would consider or recommend OC for any reason, whereas most respondents in CWE and Asia would do that only for certain social reasons or medical necessity.

Conclusion: A good understanding of OC was observed. Nationality appeared to impact opinions on appropriate indications for this procedure, though overall positive attitudes were documented.

Keywords: International attitudes; Medical egg freezing; Oocyte cryopreservation; Planned oocyte cryopreservation; Social egg freezing.