Quality of life and its association with predictors in lung transplant recipients: a latent profile analysis

Front Public Health. 2024 Apr 29:12:1355179. doi: 10.3389/fpubh.2024.1355179. eCollection 2024.

Abstract

Backgrounds: Improving quality of life (QOL) is one of the main aims of lung transplantation (LTx). There is a need to identify those who have poor quality of life early. However, research addressing inter individual quality of life variability among them is lacking. This study aims to identify group patterns in quality of life among lung transplant recipients and examine the predictors associated with quality of life subgroups.

Methods: In total, 173 lung transplant recipients were recruited from one hospital in Guangdong Province between September 2022 and August 2023. They were assessed using the Lung Transplant Quality of Life scale (LT-QOL), Mindful Attention Awareness Scale (MAAS), Life Orientation Test-Revised scale (LOT-R), and Positive and Negative Affect Scale (PANAS). Latent profile analysis was used to identify QOL subtypes, and logistic regression analysis was used to examine the associations between latent profiles and sociodemographic and psychosocial characteristics.

Results: Two distinct QOL profiles were identified: "low HRQOL" profile [N = 53 (30.94%)] and "high HRQOL" profile [N = 120 (69.06%)]. Single lung transplant recipients, and patients who reported post-transplant infection, high levels of negative emotion or low levels of mindfulness and optimism were significantly correlated with the low QOL subgroup.

Conclusion: Using the domains of the LT-QOL scale, two profiles were identified among the lung transplant recipients. Our findings highlighted that targeted intervention should be developed based on the characteristics of each latent class, and timely attention must be paid to patients who have undergone single lung transplantation, have had a hospital readmission due to infection, exhibit low levels of optimism, low levels of mindfulness or high negative emotions.

Keywords: latent profile analysis; lung transplant recipients; mindfulness; nursing; optimism; quality of life.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • China
  • Female
  • Humans
  • Latent Class Analysis
  • Lung Transplantation* / psychology
  • Male
  • Middle Aged
  • Mindfulness
  • Quality of Life* / psychology
  • Surveys and Questionnaires
  • Transplant Recipients* / psychology
  • Transplant Recipients* / statistics & numerical data

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was funded by the Key Discipline Project of Guangzhou City, Clinical Nursing Research Program of Guangdong Nursing Association in 2022 (GDKY202209).