Untreated Graves' Disease Complicated by Thyroid Storm and High-Output Cardiac Failure: A Case Report

Cureus. 2024 Apr 13;16(4):e58205. doi: 10.7759/cureus.58205. eCollection 2024 Apr.

Abstract

Thyroid storm is a rare yet critical complication of uncontrolled thyrotoxicosis, posing significant challenges in clinical management. We present the case of a 65-year-old African-American female with a medical history significant for untreated Graves' disease, hypertension, and diverticulosis, who presented with escalating abdominal pain, accompanied by nausea, vomiting, diarrhea, and chest discomfort. Upon admission, she exhibited atrial fibrillation with rapid ventricular response (RVR) and newly diagnosed high-output cardiac failure. Diagnosis of thyroid storm was confirmed through comprehensive laboratory assessments and clinical evaluation. Treatment with beta-blockers, anti-thyroid medications, and corticosteroids facilitated stabilization of her condition. This case report highlights the importance of early identification and intervention in thyroid storm to avert potential morbidity and mortality.

Keywords: abdominal pain; atrial fibrillation; cardiomegaly; clostridium difficile; graves disease; high-output heart failure; pericardial effusion; rapid ventricular response; thyroid storm; thyrotoxicosis.

Publication types

  • Case Reports