Doxycycline-Associated Ulcerative Esophagitis: A Report of a Rare Case

Cureus. 2024 Apr 11;16(4):e58079. doi: 10.7759/cureus.58079. eCollection 2024 Apr.

Abstract

This study addresses the risks of medication-induced esophageal injury through a case presentation of a 30-year-old patient treated with doxycycline. The case highlights the importance of proper medication administration and the role of endoscopic evaluation in diagnosis and management. The broader discussion emphasizes the prevalence of such injuries, especially with antibiotics, and factors influencing their occurrence. A clinical study illustrates the corrosive effect of tetracycline, highlighting the role of pH and hyperosmolar properties. The study concludes with a reminder of the critical role of healthcare professionals in recognizing and managing medication-induced esophagitis, with endoscopy as a key diagnostic tool.

Keywords: antibiotics; doxycycline; endoscopic evaluation; medication-induced esophageal injury; tetracycline.

Publication types

  • Case Reports