Risk Factors for Bladder Neck Contracture Following Transurethral Resection of the Prostate in Patients with Benign Prostatic Enlargement

Urol Int. 2024 May 13. doi: 10.1159/000539296. Online ahead of print.

Abstract

Introduction To investigate the risk factors associated with developing BNC after bipolar TURP. Methods This retrospective cohort study included patients with symptomatic BPE who underwent TURP at our institution between 2010 and 2021. Univariate and multivariate Cox regression analyses were used to evaluate the association of patient- and surgery-related factors to BNC. The preoperative urinary catheterization and resection speed with BNC were evaluated by dividing the patients into four groups as follows: (1) with or (2) without preoperative urinary catheterization and (3) high or (4) low resection speed. The risk of BNC3Y between the four groups was compared using the Kaplan-Meier analysis and log-rank tests. Results 2041 patients underwent TURP between 2010 and 2021 were enrolled. Within 3 years of surgery, 306 (15%) patients were diagnosed with BNC. COPD, congestive heart failure, preoperative urinary catheterization, and low resection speed were associated with a higher risk of BNC3Y. The Kaplan-Meier analysis and log-rank tests demonstrated an increased risk of BNC due to preoperative urinary catheterization, regardless of the resection speed. Multivariate analysis revealed that COPD and preoperative urinary catheterization were independent predictive factors for BNC. Conclusions Our study findings indicate that preoperative urinary catheterization and COPD are associated with an increased risk of BNC in patients with BPE undergoing bipolar TURP.