A commentary on the development and use of smartphone imaging devices

Biophys Rev. 2023 Dec 16;16(2):151-163. doi: 10.1007/s12551-023-01175-1. eCollection 2024 Apr.

Abstract

Current-age smartphones are known for their wide array of functionality and are now being utilized in the field of healthcare and medicine due to their proven capabilities as smartphone imaging devices (SIDs). Recent technical advancements enabled the integration of special add-on lenses with smartphones to transform them into SIDs. With the rising demand for efficient point-of-care (PoC) devices for better diagnostic applications, SIDs will be a one-stop solution. Additionally, portability, user-friendliness and low-cost make it accessible for all even at remote locations. Furthermore, improvements in resolution, magnification and field-of-view (FOV) have attracted the scientific community to use SIDs in various biomedical applications such as disease diagnosis, food quality control and pathogen detection. SIDs can be arranged in various combinational setups by using different illumination sources and optics to achieve suitable contrast and visibility of the specimen under study. This Commentary illustrates the various illumination sources used in SID and also spotlights their design and applications.

Keywords: Diagnostics; Fluorescence imaging; LED; Laser; Microscopy; Smartphone.