Gestational trophoblastic neoplasia with pulmonary embolism mimicking tuberculosis

Varuna Jethani; Sushant Khanduri; Ankit Batra; Shivam Sinha

doi:10.4103/jfmpc.jfmpc_1278_23

Gestational trophoblastic neoplasia with pulmonary embolism mimicking tuberculosis

J Family Med Prim Care. 2024 Mar;13(3):1115-1118. doi: 10.4103/jfmpc.jfmpc_1278_23. Epub 2024 Apr 4.

Authors

Varuna Jethani¹, Sushant Khanduri¹, Ankit Batra², Shivam Sinha²

Affiliations

¹ Department of Respiratory Medicine, Himalayan Institute of Medical Sciences, Jollygrant, Dehradun, Uttarakhand, India.
² Department of Medical Oncology, Himalayan Institute of Medical Sciences, Jollygrant, Dehradun, Uttarakhand, India.

Abstract

Gestational trophoblastic neoplasia (GTN) comprises a group of human neoplastic diseases that derive from fetal trophoblastic tissues. They are proliferative as well as degenerative disorders of placental elements and include complete hydatidiform mole (CHM) or partial hydatidiform mole (PHM) (90%), invasive mole (IM) (5-8%), which could also be metastatic, villous, or villous choriocarcinoma (CC) (1-2%), and placental site trophoblastic tumor (PSTT) (1-2%). We present three cases of GTN, two mimicking tuberculosis radiologically, and all three are associated with pulmonary embolism.

Keywords: B-hCG level; chemotherapy; gestational trophoblastic neoplasia; pulmonary embolism; tuberculosis.

Publication types

Case Reports