Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity

Andrea Pigorini; Pietro Avanzini; Andrei Barborica; Christian-G Bénar; Olivier David; Michele Farisco; Corey J Keller; Alfredo Manfridi; Ezequiel Mikulan; Angelique C Paulk; Nicolas Roehri; Ajay Subramanian; Serge Vulliémoz; Rina Zelmann

doi:10.1016/j.jneumeth.2024.110160

Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity

J Neurosci Methods. 2024 May 9:408:110160. doi: 10.1016/j.jneumeth.2024.110160. Online ahead of print.

Authors

Affiliations

¹ Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy; UOC Maxillo-facial Surgery and dentistry, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: andrea.pigorini@unimi.it.
² Institute of Neuroscience, Consiglio Nazionale delle Ricerche, Parma, Italy.
³ Physics Department, University of Bucharest, Bucharest, Romania.
⁴ Aix Marseille Univ, Inserm, U1106, INS, Institut de Neurosciences des Systèmes, Marseille, France.
⁵ Centre for Research Ethics and Bioethics, Department of Public Health and Caring Sciences, Uppsala University, P.O. Box 256, Uppsala, SE 751 05, Sweden; Science and Society Unit Biogem, Biology and Molecular Genetics Institute, Via Camporeale snc, Ariano Irpino, AV 83031, Italy.
⁶ Department of Psychiatry & Behavioral Sciences, Stanford University Medical Center, Stanford, CA 94305, USA; Wu Tsai Neurosciences Institute, Stanford University Medical Center, Stanford, CA 94305, USA; Veterans Affairs Palo Alto Healthcare System, and the Sierra Pacific Mental Illness, Research, Education, and Clinical Center (MIRECC), Palo Alto, CA 94394, USA.
⁷ Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
⁸ Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.
⁹ Department of Neurology and Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
¹⁰ EEG and Epilepsy Unit, Dpt of Clinical Neurosciences, Geneva University Hospitals and University of Geneva, Switzerland.
¹¹ Department of Neurology and Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: rzelmann@mgh.harvard.edu.

PMID: 38734149
DOI: 10.1016/j.jneumeth.2024.110160

Abstract

Simultaneous noninvasive and invasive electrophysiological recordings provide a unique opportunity to achieve a comprehensive understanding of human brain activity, much like a Rosetta stone for human neuroscience. In this review we focus on the increasingly-used powerful combination of intracranial electroencephalography (iEEG) with scalp electroencephalography (EEG) or magnetoencephalography (MEG). We first provide practical insight on how to achieve these technically challenging recordings. We then provide examples from clinical research on how simultaneous recordings are advancing our understanding of epilepsy. This is followed by the illustration of how human neuroscience and methodological advances could benefit from these simultaneous recordings. We conclude with a call for open data sharing and collaboration, while ensuring neuroethical approaches and argue that only with a true collaborative approach the promises of simultaneous recordings will be fulfilled.

Keywords: Hd-EEG; IEEG; Invasive and non-invasive; MEG; Simultaneous recordings.

Publication types

Review