Liver disease is a serious public health problem worldwide, affecting human health. However, there are still many unmet needs for the treatment of liver disease, especially with new therapeutic drugs. At present, there is no treatment method to eradicate the hepatitis B virus, nor are there therapeutic drugs for liver fibrosis, liver failure, and others. Chemotherapy and targeted immunotherapy are still unsatisfactory for liver cancer. This article provides an overview of the current status and challenges that arise in new drug research and development for liver diseases.
肝病在全球是一个严重的公共卫生问题，影响人类的健康，但是目前针对肝病治疗，尤其是新药治疗仍有许多未满足的需求。目前尚无根除乙型肝炎病毒的治疗方法，也无肝纤维化和肝衰竭等的治疗药物，肝癌的化疗和靶向及免疫治疗还不尽如人意。现就目前针对肝病的新药研发的现状与面临的挑战进行概述。.
Keywords: Liver disease; New drugs; Research and development.