Monoclonal antibody development advances immunological research in horses

Vet Immunol Immunopathol. 2024 May 6:272:110771. doi: 10.1016/j.vetimm.2024.110771. Online ahead of print.

Abstract

Host immune analyses require specific reagents to identify cellular and soluble components of the immune system. These immune reagents are often species-specific. For horses, various immunological tools have been developed and tested by different initiatives during the past decades. This article summarizes the development of well characterized monoclonal antibodies (mAbs) for equine immune cells, immunoglobulin isotypes, cytokines, and chemokines.

Keywords: Antibody isotypes; CD markers; Chemokines; Cytokines; Horse; Monoclonal antibodies.