Association between dynapenia and multimorbidity: A systematic review

Ann Geriatr Med Res. 2024 Apr 24. doi: 10.4235/agmr.24.0007. Online ahead of print.

Abstract

Dynapenia and multimorbidity are common health problems affecting older adults. However, few studies have systematically reviewed the association between dynapenia and multimorbidity. Therefore, this systematic review aimed to provide a comprehensive overview of studies on the association between these conditions. We searched four electronic databases for relevant articles published in July 2023. The main inclusion criteria were the following: (1) a description of dynapenia, which indicates loss of muscle strength and (2) a description of multimorbidity with two or more chronic diseases. Five studies met these inclusion criteria. In all five of these studies, the participants were community-dwelling older adults. All the studies showed an association between dynapenia and multimorbidity. The prevalence of dynapenia and multimorbidity ranged from 16% to 25.9%. The results of our systematic review demonstrated that dynapenia in older adults increases the risk of multimorbidity. We propose that interventions and reversible changes in dynapenia can prevent multimorbidity.

Keywords: Dynapenia; Multi disease; Multimorbidity; Older adults; Systematic review.