A review regarding the article 'Local versus General Anaesthesia for Transcatheter Aortic Valve Implantation (TAVI): A systematic review, meta-analysis, and trial sequential analysis of randomised and propensity-score matched studies'

Curr Probl Cardiol. 2024 Jul;49(7):102629. doi: 10.1016/j.cpcardiol.2024.102629. Epub 2024 May 7.

Abstract

Transcatheter aortic valve implantation (TAVI) is a promising treatment strategy for high-risk surgical patients, and trials investigating its effectiveness in intermediate- and lower-risk patients are underway. Data are inconsistent regarding the superiority of using local anesthesia with conscious sedation alone versus general anesthesia (GA) as the anesthesia management of choice for elderly frail patients. Historically, TAVI procedure is performed under GA with transesophageal echocardiography. This approach gives operators stable hemodynamic control of the patient and helps decrease the risk of many of the operation's documented complications, including paravalvular leak and valve malpositioning. However, some studies have criticized the dependence of GA on mechanical ventilation and an increased need for catecholamine and/or vasopressor agents. Alternatively, to further capitalize on the minimally invasive nature of TAVI, some authors have advocated for the use of local anesthesia (LA) and/or conscious sedation approach, which would decrease procedure time, length of hospital stay, and minimize the need for postoperative inotropes. Ultimately and at present, the choice of anesthesia is based on the personal experience and preference of the Heart Team involved in the TAVI procedure, which will dictate the best possible management plan for each patient. Many patients currently undergoing TAVI are elderly and have multiple comorbidities, making their care complex. Anesthetic care is shifting from GA to sedation and regional block, but life-threatening complications are still relatively common and safety during planning and conduct of these procedures by the heart team, with the anesthesiologist at the center, is paramount.

Keywords: Aortic stenosis; General anaesthesia; Local anesthesia; Transcatheter aortic valve implantation.

Publication types

  • Systematic Review
  • Meta-Analysis
  • Comparative Study
  • Letter

MeSH terms

  • Anesthesia, General* / methods
  • Anesthesia, Local* / methods
  • Aortic Valve Stenosis* / surgery
  • Humans
  • Propensity Score
  • Randomized Controlled Trials as Topic*
  • Transcatheter Aortic Valve Replacement* / methods