Application and Perspectives: Magnesium Materials in Bone Regeneration

ACS Biomater Sci Eng. 2024 May 9. doi: 10.1021/acsbiomaterials.3c01713. Online ahead of print.

Abstract

The field of bone regeneration has always been a hot and difficult research area, and there is no perfect strategy at present. As a new type of biodegradable material, magnesium alloys have excellent mechanical properties and bone promoting ability. Compared with other inert metals, magnesium alloys have significant advantages and broad application prospects in the field of bone regeneration. By searching the official Web sites and databases of various funds, this paper summarizes the research status of magnesium composites in the field of bone regeneration and introduces the latest scientific research achievements and clinical transformations of scholars in various countries and regions, such as improving the corrosion resistance of magnesium alloys by adding coatings. Finally, this paper points out the current problems and challenges, aiming to provide ideas and help for the development of new strategies for the treatment of bone defects and fractures.

Keywords: biomaterials; bone regeneration; clinical application; immune response; magnesium.

Publication types

  • Review