Duodenal-type follicular lymphoma (DFL) are uncommon, presenting in both symptomatic and asymptomatic patients, and are generally associated with a benign clinical course. Treatment options include surgery, radiation, and chemotherapy. However, many patients can be managed conservatively with little to no treatment, as 5-year progression-free survival is greater than 70%, and 5-year overall survival ranges from 80% to 94%. Here, we present a case of incidental DFL in a patient with metabolic dysfunction-associated steatohepatitis and cirrhosis. A review of the endoscopic and histologic characteristics, as well as epidemiology, risk factors, and long-term outcomes, may guide management strategies when DFL is encountered.
Keywords: MASH; b-cell; cirrhosis; follicular; gastrointestinal; lymphoma; malignancy; non-hodgkin.
© 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.