In this article for the Highlights of 2023 Series, we consider the growing understanding of mast cell heterogeneity and interactions that has developed from single cell RNA sequencing studies. We also discuss novel concepts concerning mast cell interactions with the central nervous system and evidence for their role in host defense against SARS-CoV-2 infection.
Keywords: CNS; immune defense; immune function; mast cells.
© 2024 the Australian and New Zealand Society for Immunology, Inc.