Surface dose measurement and comparison between TLD and OSLD during modified re constructive mastectomy irradiation

Biomed Phys Eng Express. 2024 May 17;10(4). doi: 10.1088/2057-1976/ad47fd.

Abstract

Radiotherapy (RT) is one of the major treatment modalities among surgery and chemotherapy for carcinoma breast. The surface dose study of modified reconstructive constructive Mastectomy (MRM) breast is important due to the heterogeneity in the body contour and the conventional treatment angle to save the lungs and heart from the radiation. These angular entries of radiation beam cause an unpredictable dose deposition on the body surface, which has to be monitored. Thermoluminescent dosimeter (TLD) or optically stimulated luminescent dosimeter (nano OSLD) are commonly preferable dosimeters for this purpose. The surface dose response of TLD and nano OSLD during MRM irradiation has been compared with the predicted dose from the treatment planning system (TPS). The study monitored 100 MRM patients by employing a total 500 dosimeters consisting of TLD (n = 250) and nano OSLD (n = 250), during irradiation from an Elekta Versa HD 6 MV Linear accelerator. The study observed a variance of 3.9% in the dose measurements for TLD and 3.2% for nano OSLD from the planned surface dose, with a median percentage dose of 44.02 for nano OSLD and 40.30 for TLD (p value 0.01). There was no discernible evidence of variation in dose measurements attributable to differences in field size or from patient to patient. Additionally, no variation was observed in dose measurements when comparing the placement of the dosimeter from central to off-centre positions. In comparison, a minor difference in dose measurements were noted between TLD and nano OSLD, The study's outcomes support the applicability of both TLD and nano OSLD as effective dosimeters during MRM breast irradiation for surface dose evaluation.

Keywords: MRM; OSLD; TLD; linear accelerator; luminescent detectors; surface dose.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Breast / radiation effects
  • Breast / surgery
  • Breast Neoplasms* / radiotherapy
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Mastectomy*
  • Middle Aged
  • Optically Stimulated Luminescence Dosimetry / methods
  • Radiation Dosage
  • Radiotherapy Dosage*
  • Radiotherapy Planning, Computer-Assisted / methods
  • Thermoluminescent Dosimetry* / methods