Cost-effectiveness of restorative treatments for permanent molars with severe molar incisor hypomineralization: perspectives for the Brazilian public health system

Clin Oral Investig. 2024 May 7;28(6):301. doi: 10.1007/s00784-024-05652-z.

Abstract

Objectives: To undertake a cost-effectiveness analysis of restorative treatments for a first permanent molar with severe molar incisor hypomineralization from the perspective of the Brazilian public system.

Materials and methods: Two models were constructed: a one-year decision tree and a ten-year Markov model, each based on a hypothetical cohort of one thousand individuals through Monte Carlo simulation. Eight restorative strategies were evaluated: high viscosity glass ionomer cement (HVGIC); encapsulated GIC; etch and rinse adhesive + composite; self-etch adhesive + composite; preformed stainless steel crown; HVGIC + etch and rinse adhesive + composite; HVGIC + self-etch adhesive + composite, and encapsulated GIC + etch and rinse adhesive + composite. Effectiveness data were sourced from the literature. Micro-costing was applied using 2022 USD market averages with a 5% variation. Incremental cost-effectiveness ratio (ICER), net monetary benefit (%NMB), and the budgetary impact were obtained.

Results: Cost-effective treatments included HVGIC (%NMB = 0%/ 0%), encapsulated GIC (%NMB = 19.4%/ 19.7%), and encapsulated GIC + etch and rinse adhesive + composite (%NMB = 23.4%/ 24.5%) at 1 year and 10 years, respectively. The benefit gain of encapsulated GIC + etch and rinse adhesive + composite in relation to encapsulated GIC was small when compared to the cost increase at 1 year (gain of 3.28% and increase of USD 24.26) and 10 years (gain of 4% and increase of USD 15.54).

Conclusion: Within the horizon and perspective analyzed, the most cost-effective treatment was encapsulated GIC restoration.

Clinical relevance: This study can provide information for decision-making.

Keywords: Cost-effectiveness analysis; Economic; Models; Molar hypomineralization; Pediatric dentistry; Restorative treatment.

MeSH terms

  • Brazil
  • Cost-Benefit Analysis*
  • Decision Trees
  • Dental Enamel Hypoplasia* / therapy
  • Dental Restoration, Permanent* / economics
  • Dental Restoration, Permanent* / methods
  • Glass Ionomer Cements* / therapeutic use
  • Humans
  • Markov Chains
  • Molar
  • Molar Hypomineralization
  • Monte Carlo Method

Substances

  • Glass Ionomer Cements