Axillary and musculocutaneous neuropathies

Handb Clin Neurol. 2024:201:135-148. doi: 10.1016/B978-0-323-90108-6.00004-1.

Abstract

This chapter covers axillary and musculocutaneous neuropathies, with a focus on clinically relevant anatomy, electrodiagnostic approaches, etiologic considerations, and management principles. Disorders of the lateral antebrachial cutaneous nerve, a derivative of the musculocutaneous nerve, are also reviewed. We emphasize the importance of objective findings, including the physical examination and electrodiagnostic evaluation in confirming the isolated involvement of each nerve which, along with the clinical history, informs etiologic considerations. Axillary and musculocutaneous neuropathies are both rare in isolation and most frequently occur in the setting of trauma. Less commonly encountered etiologies include external compression or entrapment, neoplastic involvement, or immune-mediated disorders including neuralgic amyotrophy, postsurgical inflammatory neuropathy, multifocal motor neuropathy, vasculitic neuropathy, and multifocal chronic inflammatory demyelinating polyradiculoneuropathy.

Keywords: Axillary neuropathy; Brachial plexopathy; Brachial plexus; Electromyography; Lateral antebrachial cutaneous neuropathy; Musculocutaneous neuropathy; Nerve conduction studies.

Publication types

  • Review

MeSH terms

  • Axilla
  • Electrodiagnosis / methods
  • Humans
  • Musculocutaneous Nerve*
  • Peripheral Nervous System Diseases* / diagnosis