Changes in Lung Function among Infants Born Extremely Preterm over a 20-year Period in the Post-surfactant era: A Retrospective Study

Katsuya Hirata; Takayuki Iwaibara; Masatoshi Nozaki; Narutaka Mochizuki; Shinya Hirano; Kazuko Wada

doi:10.1016/j.jpeds.2024.114082

Changes in Lung Function among Infants Born Extremely Preterm over a 20-year Period in the Post-surfactant era: A Retrospective Study

J Pediatr. 2024 Apr 30:114082. doi: 10.1016/j.jpeds.2024.114082. Online ahead of print.

Authors

Katsuya Hirata¹, Takayuki Iwaibara², Masatoshi Nozaki², Narutaka Mochizuki², Shinya Hirano², Kazuko Wada²

Affiliations

¹ Department of Neonatal Medicine, Osaka Women's and Children's Hospital. Electronic address: khirata0513@gmail.com.
² Department of Neonatal Medicine, Osaka Women's and Children's Hospital.

PMID: 38697609
DOI: 10.1016/j.jpeds.2024.114082

Abstract

Lung function was assessed at 8 years in 308 infants born extremely preterm between 1994 and 2013. Although lung function remained unchanged those infants born at 22 through 25 weeks, those who were born at 26 to 27 weeks showed a significant improvement over the past two decades.

Keywords: bronchopulmonary dysplasia; chronic lung disease; lung function; spirometry.