Keep calm and make neurons: The effects of glucocorticoids on human cortical neurogenesis

Neuron. 2024 May 1;112(9):1373-1375. doi: 10.1016/j.neuron.2024.04.004.

Abstract

Maternal well-being is important for the development of the fetus, with a key influence on its nervous system. In this issue of Neuron, Krontira et al.1 implicate glucocorticoids, the stress hormones, in the regulation of neural stem cell identity and proliferation, with long-lasting consequences on brain architecture and educational attainment.

MeSH terms

  • Cerebral Cortex / cytology
  • Cerebral Cortex / drug effects
  • Glucocorticoids* / pharmacology
  • Humans
  • Neural Stem Cells / drug effects
  • Neurogenesis* / drug effects
  • Neurogenesis* / physiology
  • Neurons / drug effects
  • Neurons / physiology

Substances

  • Glucocorticoids