Gravi-D peptide disrupts HDAC11 association with an AKAP to stimulate adipocyte thermogenic signaling

J Clin Invest. 2024 May 1;134(9):e177726. doi: 10.1172/JCI177726.

Authors

Emma L Robinson^{1

2}, Charles A Tharp^{1

2}, Rushita A Bagchi^{1

2}, Timothy A McKinsey^{1

2}

Affiliations

¹ Department of Medicine, Division of Cardiology and.
² Consortium for Fibrosis Research & Translation, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

No abstract available

Keywords: Adipose tissue; Cell biology; Signal transduction; Therapeutics.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

A Kinase Anchor Proteins* / genetics
A Kinase Anchor Proteins* / metabolism
Adipocytes / metabolism
Animals
Histone Deacetylases* / genetics
Histone Deacetylases* / metabolism
Humans
Mice
Signal Transduction*
Thermogenesis*

Substances

Histone Deacetylases
A Kinase Anchor Proteins