Exploring stakeholders' perspectives on antibiogram use, development, and implementation in residential aged care settings

Dipti Khatri; Nazanin Falconer; Soraia de Camargo Catapan; Sonali Coulter; Leonard C Gray; David L Paterson; Christopher Freeman

doi:10.1016/j.sapharm.2024.04.011

Exploring stakeholders' perspectives on antibiogram use, development, and implementation in residential aged care settings

Res Social Adm Pharm. 2024 Apr 25:S1551-7411(24)00125-6. doi: 10.1016/j.sapharm.2024.04.011. Online ahead of print.

Authors

Dipti Khatri¹, Nazanin Falconer², Soraia de Camargo Catapan³, Sonali Coulter⁴, Leonard C Gray⁵, David L Paterson⁶, Christopher Freeman⁷

Affiliations

¹ UQ Centre for Health Service Research (CHSR), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia. Electronic address: d.khatri@uq.edu.au.
² UQ Centre for Health Service Research (CHSR), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia; School of Pharmacy, The University of Queensland, Woolloongabba, QLD, Australia; Princess Alexandra Hospital, Metro South Health, Woolloongabba, QLD, Australia.
³ UQ Centre for Health Service Research (CHSR), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia; UQ Centre for Online Health (COH), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia.
⁴ Pathology Queensland, Microbiology Queensland Public Health and Scientific Services, Herston, QLD, Australia.
⁵ UQ Centre for Health Service Research (CHSR), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia.
⁶ ADVANCE-ID, Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Faculty of Medicine, The University of Queensland, Herston, QLD, Australia; Metro North Hospital and Health Service, Herston, QLD, Australia.
⁷ School of Pharmacy, The University of Queensland, Woolloongabba, QLD, Australia; Faculty of Medicine, The University of Queensland, Herston, QLD, Australia; Metro North Hospital and Health Service, Herston, QLD, Australia.

PMID: 38688774
DOI: 10.1016/j.sapharm.2024.04.011

Abstract

Background: Knowledge of local antibiotic resistance data provided by antibiograms (cumulative-antimicrobial-susceptibility-tests) can assist prescribers to make appropriate empirical antibiotic choices.

Objective: This study explored the perceptions and knowledge of key stakeholders about the role of antibiograms in residential aged care facilities (RACF), and to understand barriers and enablers of antibiogram development and implementation in this setting.

Method: Semi-structured interviews were conducted with aged-care health professionals ('end-users') and antibiogram content experts. This study was conducted in Queensland, Australia in 2023. Using qualitative techniques, framework thematic analysis was used to identify themes, which were mapped to the 'Integrated Promoting Action on Research Implementation in Health Services' framework constructs.

Results: Twenty interviews were conducted comprising of five 'content-experts' and fifteen 'end-users'. Five themes were identified which indicated lack of knowledge about how to use antibiograms, and its availability. Potential insufficient data was the primary issue identified by content experts with regards to feasibility of annual antibiograms. Pragmatic solutions were offered, such as pooling pathology data from facilities in the same geographical location, extending antibiogram data to two-or three-yearly, or utilising local hospital antibiograms. Presenting antibiogram data in a mode and format suiting preferences of individual users would encourage uptake and improve usability. Antimicrobial stewardship (AMS) champions and pharmacists were highlighted as drivers of educating and promoting antibiogram use.

Conclusion: Clinicians recognised the potential role of antibiograms in improving empirical antibiotic prescribing choices. Establishing their baseline knowledge provides an essential starting point for the education needs of this group. This study provides practical recommendations regarding the presentation of antibiograms to ensure appropriate use and uptake as an AMS tool in RACFs. Pragmatic solutions suggested to overcome challenges of antibiogram development for RACFs should be applied and evaluated to determine feasibility of RACF-specific antibiograms.

Keywords: Aged care; Antibiogram; Antibiotic; Framework analysis; Implementation; i-PARIHS.