Advanced intraocular retinoblastoma: evolving criteria for group E disease

Can J Ophthalmol. 2024 Apr 27:S0008-4182(24)00068-1. doi: 10.1016/j.jcjo.2024.03.005. Online ahead of print.

Abstract

With evolving criteria for classifying intraocular retinoblastoma (RB) from International Intraocular Retinoblastoma Classification (IIRC, 2005) to International Classification of Retinoblastoma (ICRB, 2006), there have been changes in the inclusion criteria for groups E eyes that have not been widely recognized. This brief review highlights issues with the current classification systems (ICRB and IIRC) and layouts a theoretical framework arguing for merging of 2 existing classifications into 1 and subdividing the expanded group E RB, thereby preserving the possibility to reanalyze existing published data.

Publication types

  • Letter