Bibliometric evaluation of global trends and characteristics of RNA methylation during angiogenesis

Bingyan Li; Zicong Wang; Haixiang Zhou; Wei Tan; Jingling Zou; Yun Li; Shigeo Yoshida; Yedi Zhou

doi:10.1016/j.heliyon.2024.e29817

Bibliometric evaluation of global trends and characteristics of RNA methylation during angiogenesis

Heliyon. 2024 Apr 16;10(8):e29817. doi: 10.1016/j.heliyon.2024.e29817. eCollection 2024 Apr 30.

Authors

Bingyan Li^{1

2

3}, Zicong Wang^{1

2

3}, Haixiang Zhou^{1

2

3}, Wei Tan^{1

2

3}, Jingling Zou^{1

2

3}, Yun Li^{1

2

3}, Shigeo Yoshida⁴, Yedi Zhou^{1

2

3}

Affiliations

¹ Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
² Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan, 410011, China.
³ National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
⁴ Department of Ophthalmology, Kurume University School of Medicine, Kurume, Fukuoka, 830-0011, Japan.

Abstract

Background: RNA methylation is involved in major life processes. Angiogenesis is a normal phenomenon that occurs constantly in the bodies of all mammals, once it is aberrant or something goes wrong, it may lead to pathological changes. The bibliometric analysis could produce a comprehensive overview of RNA methylation during angiogenesis.

Methods: The Web of Science Core Collection (WoSCC) database was used to screen publications about RNA methylation during angiogenesis from Jan 1, 2000 to Nov 24, 2022. Bibliometric and visualization analyses were conducted to understand publication trends by CiteSpace and VOSviewer.

Results: In total, 382 publications from 2000 to 2022 were included in the bibliometric and visualization analyses. On the whole, the number of publications had exponential growth. China was the country and Sun Yat-Sen University was the university associated with the largest number of publications, although publications from the United Kingdom and Soochow University were currently having the strongest impact. Cancer was the most studied topic in this field, and N6-methyladenosine is the most studied RNA methylation type.

Conclusion: There is a continuously increasing trend in publications related to RNA methylation and angiogenesis, which has attracted much attention, particularly since 2011. RNA methylation might be a promising target in the investigation of pathological angiogenesis and related disorders, which deserves further investigation.

Keywords: Angiogenesis; Bibliometric analysis; CiteSpace; RNA methylation; VOSviewer.