Key topics for making decisions on decorporation terapies

Abstract

Decorporation therapies increase the excretion of the incorporated material and therefore may reduce the probability of the occurrence of stochastic effects and may avoid deterministic effects in persons internally contaminated with radionuclides. The decision to initiate decorporation therapy should consider the effects of treatment in relation to the benefit provided. The literature presents threshold values above which treatment is recommended. The objective of this work is to collect and summarize recommendations on decorporation therapy. Ten key topics are presented for consideration by a multidisciplinary team when assessing the risk-benefit balance for performing decorporation therapy.