Correlating Jaw Bone Growth and Nasal Morphology Among Adult Patients With Cleft Lip and Palate: A Retrospective Cephalometric Study

J Craniofac Surg. 2024 Jun 1;35(4):e405-e407. doi: 10.1097/SCS.0000000000010102. Epub 2024 Apr 26.

Abstract

This retrospective cross-sectional study reviewed adult patients with operated cleft lip and/or palate (CL/P) and normal control, and performed comprehensive craniofacial and nasal morphological analyses based on lateral cephalometric radiographs. Pearson or Spearman correlation coefficient assessed intraclass correlation. Seven hundred fifty-seven operated patients with CL/P, and 165 noncleft normal controls were enrolled. Among the normal and CL/P groups, S-N-A angle registered positive correlations with nasal base prominence (S-N'-Sn, degrees). Upper facial height (N-ANS, mm) had positive correlations with nasal dorsum length (N'-Prn, mm) and nasal bone length (N-Na, mm). Although in patients with bilateral cleft lip and palate, there were moderate negative correlations ( r =-0.541, P <0.05) with soft tissue facial profile angle (FH-N'Pog', degree) and nasolabial angle (Cm-Sn-ULA, degree). Correlation exists between the morphology of jaw bones and external nose among patients with CL/P. Maxillary sagittal insufficiency is associated with concave nasal profile, and maxilla height is associated with nasal length.

MeSH terms

  • Adolescent
  • Adult
  • Case-Control Studies
  • Cephalometry*
  • Cleft Lip* / diagnostic imaging
  • Cleft Lip* / pathology
  • Cleft Lip* / surgery
  • Cleft Palate* / diagnostic imaging
  • Cleft Palate* / pathology
  • Cleft Palate* / surgery
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Maxilla / diagnostic imaging
  • Maxilla / pathology
  • Nose* / anatomy & histology
  • Nose* / diagnostic imaging
  • Nose* / pathology
  • Retrospective Studies