Indocyanine green (ICG)-guided robotic resection for liver adenoma: combined technologies for precision surgery

Updates Surg. 2024 Jun;76(3):1105-1108. doi: 10.1007/s13304-024-01840-4. Epub 2024 Apr 19.

Abstract

HCA resection is crucial to prevent bleeding and malignant transformation. The aim of this study was to enhance the precision of tumor resection in hepatocellular adenoma (HCA) through the combination of intraoperative ultrasound (IOUS) and indocyanine green (ICG) fluorescence imaging. ICG was intravenously injected 24 h before surgery, enabling positive staining of HCA nodules. IOUS guided the parenchymal transection performed using the RoboLap approach. IOUS combined with ICG effectively demarcated lesions, allowing precision surgery while sparing healthy liver tissue. Intraoperative frozen examination further validated the potential of ICG to identify previously undetected lesions. The study showed promising advantages of ICG in HCA resections, potentially reducing the risk of recurrence and malignant transformation. The combined robotic and laparoscopic approach improved the feasibility of parenchymal-sparing surgery, offering a cautious assessment of HCA lesions.

Keywords: Hepatocellular adenoma; Indocyanine green; Intraoperative ultrasound; Liver surgery; Minimally invasive liver surgery; Robotic liver surgery.

MeSH terms

  • Adenoma, Liver Cell / diagnostic imaging
  • Adenoma, Liver Cell / surgery
  • Coloring Agents / administration & dosage
  • Female
  • Hepatectomy / methods
  • Humans
  • Indocyanine Green* / administration & dosage
  • Laparoscopy / methods
  • Liver Neoplasms* / surgery
  • Male
  • Middle Aged
  • Optical Imaging / methods
  • Robotic Surgical Procedures* / methods
  • Surgery, Computer-Assisted / methods

Substances

  • Indocyanine Green
  • Coloring Agents