Advances in rapid point-of-care virus testing

Analyst. 2024 Apr 29;149(9):2507-2525. doi: 10.1039/d4an00238e.

Abstract

Outbreaks of viral diseases seriously jeopardize people's health and cause huge economic losses. At the same time, virology provides a new perspective for biology, molecular biology and cancer research, and it is important to study the discovered viruses with potential applications. Therefore, the development of immediate and rapid viral detection methods for the prevention and treatment of viral diseases as well as the study of viruses has attracted extensive attention from scientists. With the continuous progress of science and technology, especially in the field of bioanalysis, a series of new detection techniques have been applied to the on-site rapid detection of viruses, which has become a powerful approach for human beings to fight against viruses. In this paper, the latest research progress of rapid point-of-care detection of viral nucleic acids, antigens and antibodies is presented. In addition, the advantages and disadvantages of these technologies are discussed from the perspective of practical application requirements. Finally, the problems and challenges faced by rapid viral detection methods and their development prospects are discussed.

Publication types

  • Review

MeSH terms

  • Antibodies, Viral / analysis
  • Antibodies, Viral / immunology
  • Antigens, Viral / analysis
  • Biosensing Techniques / methods
  • Humans
  • Point-of-Care Systems
  • Point-of-Care Testing*
  • RNA, Viral / analysis
  • RNA, Viral / genetics
  • Virus Diseases / diagnosis
  • Viruses* / genetics
  • Viruses* / isolation & purification

Substances

  • Antigens, Viral
  • Antibodies, Viral
  • RNA, Viral