Efficacy and safety of excimer light (308 nm) in the treatment of pityriasis lichenoides chronica

Photodermatol Photoimmunol Photomed. 2024 May;40(3):e12964. doi: 10.1111/phpp.12964.

Abstract

Introduction: Pityriasis lichenoides chronica is the chronic end of the spectrum of pityriasis lichenoides which have several forms of papulosuamous conditions. Several treatments obtained complete clearance of the condition including phototherapy and specifically narrow band ultraviolet B. The Excimer light 308 is a monochromatic light that acts within the ultraviolet B wavelength and used as a targeted phototherapy in several skin conditions.

Methods: Thirty-four patients with histopathologically diagnosed pityriasis lichenoides chronica underwent treatment with biweekly sessions of excimer light 308 nm. Treatment continued until complete clearance was obtained or to a maximum of 48 sessions (24 weeks).

Results: Thirty-one patients obtained complete clearance with no recurrence till the end of the study period, two patients had partial response and only one patient showed poor response to treatment.

Conclusion: Excimer light can be a safe and effective treatment of pityriasis lichinoides chronica in different ages and genders.

Keywords: excimer; phototherapy; pityriasis lichenoides.

MeSH terms

  • Female
  • Humans
  • Kinetics
  • Male
  • Phototherapy
  • Pityriasis Lichenoides* / radiotherapy