Objectives: This study aimed to analyze the psychological status and quality of life (QoL) of patients with advanced lung cancer and assess the impact of continuous nursing intervention on these parameters.
Methods: A total of 160 advanced lung cancer patients were randomly assigned to a control group or a study group, with 80 patients in each. The control group received the routine nursing intervention, while the study group received the continuous nursing intervention, including health record establishment, regular follow-ups, diet guidance, health knowledge education, psychological counseling, and work and rest guidance. Inflammatory markers (IL-6, TNF-α, PGE2, and SP), Spitzer Quality of Life Index (SQLI), anxiety and depression self-evaluation scales, Visual Analogue Scale (VAS) for pain, and patient satisfaction were measured before and after 4 weeks of intervention.
Results: Post-intervention, the study group showed a significant reduction in serum IL-6 and TNF-α levels (P < .001), improved SQLI scores (P = .002), and lower anxiety and depression scores (P < .001) compared to the control group. A significant negative correlation between psychological status and QoL was observed (P < .001). The study group also reported lower VAS pain scores (P < .001) and higher patient satisfaction (P = .000) after the intervention.
Conclusions: Continuous nursing intervention has significantly improved psychological well-being, alleviated pain, and enhanced the overall quality of life for patients facing advanced lung cancer. These results indicate that a comprehensive and sustained nursing intervention strategy can serve as an effective approach to improve the well-being of individuals navigating advanced lung cancer during chemotherapy.