CXCR4 Antagonist in HPV5-Associated Perianal Squamous-Cell Carcinoma

N Engl J Med. 2024 Apr 11;390(14):1339-1341. doi: 10.1056/NEJMc2213180.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents* / therapeutic use
  • Antiviral Agents* / therapeutic use
  • Anus Neoplasms* / drug therapy
  • Anus Neoplasms* / virology
  • Betapapillomavirus*
  • Carcinoma, Squamous Cell* / drug therapy
  • Carcinoma, Squamous Cell* / virology
  • Gain of Function Mutation
  • Humans
  • Papillomavirus Infections* / complications
  • Papillomavirus Infections* / drug therapy
  • Papillomavirus Infections* / virology
  • Primary Immunodeficiency Diseases / drug therapy
  • Primary Immunodeficiency Diseases / genetics
  • Primary Immunodeficiency Diseases / virology
  • Receptors, CXCR4 / antagonists & inhibitors
  • Warts / drug therapy
  • Warts / genetics
  • Warts / virology

Substances

  • Antineoplastic Agents
  • Antiviral Agents
  • CXCR4 protein, human
  • plerixafor
  • Receptors, CXCR4

Supplementary concepts

  • WHIM syndrome