Solid Pseudo-papillary Neoplasia: A Rare Malignancy of the Pancreas

Biplov Adhikari; Robert Jones; Christopher J Haas

doi:10.55729/2000-9666.1254

Solid Pseudo-papillary Neoplasia: A Rare Malignancy of the Pancreas

J Community Hosp Intern Med Perspect. 2023 Nov 4;13(6):35-38. doi: 10.55729/2000-9666.1254. eCollection 2023.

Authors

Biplov Adhikari¹, Robert Jones², Christopher J Haas^{1

3}

Affiliations

¹ Medstar Health Internal Medicine Residency Training Program, Baltimore, MD, USA.
² Department of Pathology, Medstar Franklin Square Medical Center, Baltimore, MD, USA.
³ Department of Medicine, Georgetown University Medical Center, Washington, DC, USA.

Abstract

Solid pseudopapillary neoplasms (SPNs) are exceedingly rare type of exocrine pancreatic malignancy, representing only 0.9%-2.7% of all exocrine pancreatic malignancies. They predominantly affect young women and unlike other pancreatic malignancies, they have excellent prognoses with 5-year survival following surgical resection approaching 97%. Given the rarity of the disease, little is known about their histopathogenesis as they do not harbor similar genetic mutational abnormalities like other pancreatic tumors. We describe a rare case of SPN in a young female who was found to have the rare diagnosis during the work up for deranged liver function tests.

Keywords: Exocrine malignancy; Low-grade tumors; Pancreas; Rare tumors; Solid pseudopapillary neoplasm.

Publication types

Case Reports