Platelet-rich plasma (PRP) in nerve repair

Regen Ther. 2024 Apr 4:27:244-250. doi: 10.1016/j.reth.2024.03.017. eCollection 2024 Dec.

Abstract

Platelet-rich plasma (PRP) has the capability of assisting in the recovery of damaged tissues by releasing a variety of biologically active factors to initiate a hemostatic cascade reaction and promote the synthesis of new connective tissue and revascularization. It is now widely used for tissue engineering repair. In addition, PRP has demonstrated nerve repair and pain relief, and has been studied and applied to the facial nerve, median nerve, sciatic nerve, and central nerve. These suggest that PRP injection therapy has a positive effect on nerve repair. This indicates that PRP has high clinical value and potential application in nerve repair. It is worthwhile for scientists and medical workers to further explore and study PRP to expand its application in nerve repair, and to provide a more reliable scientific basis for the opening of a new approach to nerve repair.

Keywords: Nerve injury; Nerve repair; Platelet-rich plasma.

Publication types

  • Review