The relationship between sleep quality and gait in people with multiple sclerosis: A pilot study

Wlla Abedalaziz; Alham Al-Sharman; Aseel Aburub; Mariem Syrine Latrous; Patrick Esser; Helen Dawes; Khalid El-Salem; Hanan Khalil

doi:10.1142/S1013702523500129

The relationship between sleep quality and gait in people with multiple sclerosis: A pilot study

Hong Kong Physiother J. 2024 Jun;44(1):11-19. doi: 10.1142/S1013702523500129. Epub 2023 May 19.

Authors

Wlla Abedalaziz¹, Alham Al-Sharman^{1

2

3}, Aseel Aburub⁴, Mariem Syrine Latrous⁵, Patrick Esser⁶, Helen Dawes⁷, Khalid El-Salem⁸, Hanan Khalil⁵

Affiliations

¹ Faculty of Applied Medical Sciences, Department of Rehabilitation Sciences, Jordan University of Science and Technology, Irbid, Jordan.
² College of Health Sciences, Physiotherapy Department, University of Sharjah, Sharjah, UAE.
³ aal-sharman@sharjah.ac.ae.
⁴ Department of Physiotherapy, Applied Science Private University, Amman, Jordan.
⁵ Department of Physical Therapy and Rehabilitation Sciences College of Health Sciences, QU health, Qatar University, Doha, Qatar.
⁶ Centre for Movement, Occupation and Rehabilitation Sciences, Oxford Brookes University, Oxford, UK.
⁷ NIHR Exeter BRC, Medical School, University of Exeter, UK.
⁸ Faculty of Medicine, Department of Neurosciences Jordan University of Science and Technology, Irbid, Jordan.

Abstract

Background: Gait deficits are common among people with multiple sclerosis (PwMS). Therefore, investigating factors that may influence walking in PwMS is important. Previous studies in older adults and other neurological populations demonstrated the relationship between sleep quality and gait performance. Despite the fact that the prevalence of poor sleep quality is very high among PwMS, little is known about the effect of sleep quality on gait among PwMS.

Objective: This study aimed to explore the relationship between sleep quality and gait performance in PwMS.

Methods: Forty-one PwMS participated in the study between February 2019 and December 2019. Participants were asked to walk at a self-selected speed over 10 m with an inertial measurement unit (IMU) attached over the back. Walking speed, step length (left and right), and step time were calculated. Sleep was estimated objectively using a wrist-worn triaxle-accelerometer; the derived parameters were sleep efficiency (SE) and the number of awakening after sleep onset (NASO).

Results: SE significantly correlated with step length ( $p = 0.02$ ). Furthermore, the NASO significantly correlated with gait speed ( $p = 0.03$ ), and step-time ( $p = 0.02$ ). These correlations remained significant even after adjusting for age and disease duration.

Conclusion: We observed that when corrected for disease duration and age there were relationships between NASO and SE to gait parameters; these observations warrant further investigations.

Keywords: Multiple sclerosis; gait; sleep quality.