Epinephrine also acts on beta cells and insulin secretion

World J Clin Cases. 2024 Mar 26;12(9):1712-1713. doi: 10.12998/wjcc.v12.i9.1712.

Abstract

In a recent review examining neurotransmitter modulation of insulin secretion, the significant impact of epinephrine was not addressed. Its primary action involves inhibiting insulin release via alpha-adrenergic receptors, thereby reducing the response to insulin secretion stimulators, through the activation of K+ channels and resulting in membrane hyperpolarization in beta cells.

Keywords: Epinephrine; Glucose; Human; Insulin; Islets.